Women's Health Library

Every article, presentation, spotlight, and news item we've tagged to Women's Health.

All Library Articles Presentations Spotlights News

Showing 1–23 of 23

Longevity.TechnologyMar 23, 2026

Stop treating women as an exception in aging science

Aging science built primarily on male biology has systematically misunderstood female physiology, leading to ineffective or harmful optimization strategies for women. A female-centered approach recognizes that women's hormonal cycles are rhythmic rather than erratic, and that sex-based differences in metabolism, hormone production, and social bonding represent distinct biological advantages requiring tailored intervention.

LT WireMay 11, 2026

Function Health pushes comprehensive diagnostics, hormone testing

Function Health positions comprehensive lab testing—160+ markers including metabolic and hormonal panels—as a foundation for preventive health monitoring, with emphasis on insulin, cortisol, thyroid, and leptin assessment to detect metabolic dysregulation earlier than standard screening. The model links biomarker tracking to lifestyle factors to inform individualized health optimization and support longitudinal monitoring.

Longevity.TechnologyFeb 18, 2026

Menopause linked to brain structure shifts

Post-menopausal women show measurable reductions in gray matter volume within memory and emotion-regulating brain regions, correlating with increased anxiety, depression, and sleep disruption. This structural shift represents a neuroendocrine transition point with downstream implications for cognitive resilience and cardiometabolic risk in aging.

Nature AgingMar 11, 2026

Microfluidics device recovers oocytes for IVF

A microfluidics device enables recovery of immature oocytes from ovarian tissue, expanding the pool of viable eggs available for fertility preservation and IVF. This technology addresses a critical bottleneck in reproductive medicine by recovering oocytes that conventional methods miss, with direct implications for fertility outcomes across age groups.

LifeSpan.ioFeb 25, 2026

Menopausal Hormone Therapy Does Not Increase Mortality

An analysis of over 800,000 Danish women found no association between menopausal hormone therapy and increased all-cause mortality over 7-21 years of follow-up. This challenges the prevailing safety concerns that emerged from earlier studies and suggests the risk-benefit calculation for hormone therapy in perimenopausal women warrants reassessment based on individual clinical context.

Nature AgingApr 29, 2026

Multimodal data analysis reveals asynchronous aging dynamics across female reproductive organs

Deep learning analysis of histological and transcriptomic data from over 300 female donors reveals that reproductive organs age asynchronously rather than in lockstep, with menopause functioning as a critical inflection point detectable in circulating protein signatures. This challenges the assumption of synchronized aging across organ systems and identifies tissue-specific vulnerability windows relevant to longevity and disease prevention.

Nature - npj AgingMar 3, 2026

Aging and increased cancer risk: exploring the potential of LE8 score to mitigate risk

The LE8 score—a composite measure of eight cardiovascular and lifestyle factors—independently predicts cancer risk across aging populations. This relationship suggests that modifiable health behaviors affecting circulation, metabolic function, and systemic resilience substantially influence cancer development trajectories.

Longevity.TechnologyMar 4, 2026

Richter sharpens ovarian aging focus following Celmatix asset deal

Gedeon Richter acquired Celmatix's women's health portfolio, adding programs targeting ovarian aging, endometriosis, and fertility dysfunction. This transaction reflects growing recognition that ovarian function is a systemic health determinant and an investable axis within longevity science.

Wiley Aging CellApr 9, 2026

A Circadian Trough in Glucocorticoid Signaling Is Essential for Bone Health in Mice

Circadian glucocorticoid rhythm—specifically the daily trough when cortisol signaling drops—is essential for bone formation and structural integrity. Flattening this rhythm induces osteoporosis even without elevated overall cortisol, and reinstating the trough at its natural circadian timing prevents bone loss.

Longevity.TechnologyApr 21, 2026

Could osteoporosis meds prevent aneurysms?

Age-related mutations in blood-forming stem cells (clonal hematopoiesis) appear to drive aortic aneurysm progression through a bone-remodeling pathway hijacked in vascular tissue. Existing osteoporosis medications targeting this pathway slowed aneurysm growth in animal models, suggesting a repurposing opportunity for a condition currently lacking pharmacological interventions.

Longevity.TechnologyFeb 3, 2026

Xella secures $3.7m to put women first in health and longevity

Xella Health has secured $3.7 million in pre-seed funding to build a precision health platform that decodes women's biological signals through menstrual fluid analysis alongside blood testing, combined with longitudinal tracking and clinician guidance. This approach shifts women's healthcare from reactive treatment to early detection and prevention, with direct implications for hormone health, fertility, disease risk stratification, and long-term healthspan outcomes during critical life transitions like perimenopause.

LifeSpan.ioMar 6, 2026

Fat Composition Affects T Cell-Mediated Immunity

The ratio of polyunsaturated to monounsaturated fatty acids in the diet determines T cell susceptibility to ferroptosis, an iron-dependent form of cell death that regulates anti-tumor immunity, antibody production, and immune memory. Mice fed diets with low PUFA-to-MUFA ratios retained significantly more functional T cells and mounted stronger immune responses.

Longevity.TechnologyApr 21, 2026

Hone Health adds DEXA scans to personalized longevity platform

Hone Health integrated clinical-grade DEXA scans into its personalized longevity platform, enabling physicians to assess body composition changes—muscle, fat, and bone density—alongside metabolic and hormonal data. This shift from reactive screening to proactive monitoring allows earlier detection of metabolic drift and interventions before functional decline.

LT WireApr 16, 2026

Hone Health integrates BodySpec DEXA scans into longevity OS

Hone Health integrated BodySpec DEXA scanning into its longevity platform, enabling real-time body composition, bone density, and metabolic rate assessment within clinical care plans. This shift moves bone health screening from reactive post-65 assessment to proactive longitudinal tracking across younger populations.

Nature - npj AgingApr 23, 2026

Reduction of glycation stress as a geroscience intervention: protocol for a pilot RCT in postmenopausal women

A pilot randomized controlled trial investigates whether reducing glycation stress—the accumulation of sugar-derived damage to proteins—can slow aging markers in postmenopausal women. Glycation is a hallmark of aging that accelerates decline across multiple physiological systems, making this intervention relevant to the practical toolkit of longevity medicine.

Longevity.TechnologyMar 19, 2026

Wisp widens telehealth model with women-centric longevity

Wisp, a women-focused telehealth platform, has launched a longevity category offering NAD+, glutathione, and low-dose naltrexone through clinician-guided care rather than biohacking positioning. The move addresses a significant gap: 75% of women prioritize long-term health, yet only 11% feel current digital tools provide meaningful control over aging outcomes.

Nature - npj AgingApr 4, 2026

Extracellular matrix: new insights into its role in female reproductive aging and potential therapeutic strategies

The extracellular matrix—the structural scaffold surrounding reproductive tissues—undergoes progressive degradation during female reproductive aging, compromising ovarian function and fertility. Targeting matrix preservation and remodeling represents a mechanistic approach to extending reproductive lifespan and potentially supporting broader aging-related outcomes.

Wiley Aging CellFeb 26, 2026

Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice

Oxidative stress in oocytes from aged female mice triggers lipid accumulation and metabolic alterations that persist through three generations, with offspring developing compensatory antioxidant responses in lipid-rich tissues. This demonstrates that maternal aging imprints metabolic dysfunction on descendants independent of direct genetic mutation.

Peter Attia MDApr 28, 2026

Reducing cardiovascular risk: a playbook for lipid-lowering pharmacotherapy

A systematic approach to lipid-lowering pharmacotherapy uses risk stratification and a six-step protocol to guide drug selection and escalation, optimizing cardiovascular protection across heterogeneous patient populations. This framework addresses the gap between guideline recommendations and individualized clinical decision-making in managing atherosclerotic cardiovascular disease risk.

Longevity.TechnologyMar 24, 2026

NOVOS trial explores vascular aging markers

A randomized, double-blind, placebo-controlled trial in 43 healthy adults over 40 found that a multi-component nutritional intervention improved endothelial function by 2.9%, reduced arterial stiffness by 1.18 m/s, and lowered systolic blood pressure by 6.1 mmHg over six months. These improvements in vascular function markers suggest the intervention may address structural and functional aging of the arterial system, with effect sizes comparable to or exceeding those from exercise interventions.

LT WireFeb 22, 2026

Novos trial shows cardiovascular benefits in aging adults

A Novos clinical trial demonstrated statistically significant reductions in systolic and diastolic blood pressure, improved lipid profiles, and favorable shifts in metabolic markers among adults over 40 following the company's integrated lifestyle and metabolic support program. These findings support multimodal intervention as an approach to reducing established cardiovascular risk factors associated with aging.

Peter Attia MDApr 20, 2026

#388 — Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives

Current PSA-based prostate cancer screening protocols miss clinically significant cancers and fail to distinguish aggressive from indolent disease, reducing detection effectiveness. Modern biomarkers and imaging technologies enable earlier identification of aggressive tumors when intervention is most effective, fundamentally altering outcomes for men at risk.

Nature AgingMar 3, 2026

Estropausal gut microbiota transplant improves measures of ovarian function in adult mice

Transplanting gut microbiota from aging female mice into young adults restored ovarian hormone profiles, follicle development, and fertility markers, establishing a causal relationship between age-related changes in the microbiome and ovarian function decline. This demonstrates that microbiota composition directly regulates reproductive capacity independent of chronological age.

Biological EDGE

Biohacking Starts With NO