What Is Longevity

Therapies and Protocols

Clinical and at-home therapies used in longevity practice: IV therapy, peptides, hormone optimization, hyperbaric oxygen, red light, ozone, and dozens more. What each does, who it suits, and what the evidence shows.

Featured Library in Therapies and Protocols

ArticleJan 25, 2026

How Electromagnetic Fields Support Your Body's Natural Recovery Systems

Discover how electromagnetic pulses recharge your cells' natural voltage, enhancing nutrient transport and accelerating recovery. Nearly two decades of PEMF innovation supporting millions worldwide.

ArticleFeb 12, 2026

Oxygen Under Pressure: How Hyperbaric Therapy Supports Recovery at the Cellular Level

Hyperbaric oxygen therapy leverages a simple physics principle to deliver oxygen deep into tissues where recovery and repair demand it most. Here's how increased pressure supports cellular energy, circulation, and regeneration, and where it fits in a whole-system longevity strategy.

ArticleJan 19, 2026

The Cellular Energy Upgrade: How PEMF Therapy Optimizes Your Body's Power Grid

PEMF therapy addresses cellular energy production by restoring optimal bioelectric function, offering a research-backed approach to enhanced vitality and recovery.

PresentationFeb 12, 2026

Breathing at Depth: How Pressure Transforms Your Cellular Recovery

Dr. Jason Sonners reveals how hyperbaric oxygen therapy fundamentally transforms cellular recovery through the physics of pressure. Drawing on 17 years of clinical experience and current PhD research in molecular biology, he demystifies how pressurized oxygen bypasses normal physiological limits to deliver therapeutic benefits unavailable through any other modality. This session breaks down the molecular mechanisms behind HBOT's effects on ATP production, stem cell mobilization, inflammation reduction, and tissue regeneration—explaining why this underutilized therapy deserves a central role in performance optimization and longevity protocols.

ArticleFeb 6, 2026

Full Spectrum Infrared: Why Your Cells Respond to Light Like Plants

Your mitochondria contain light-sensitive proteins that trigger cellular repair and energy production when exposed to specific infrared wavelengths. Modern indoor living has created a light deficiency that affects everything from energy to immunity.

ArticleFeb 8, 2026

How Electromagnetic Fields Support Your Body's Natural Healing Rhythms

Discover how combining PEMF therapy with sound frequencies can restore cellular resonance, supporting everything from mitochondrial function to nervous system regulation in a practical home-use system.

Topics in Therapies and Protocols

Acoustic Wave Therapy

Acoustic wave therapy uses pressure waves to stimulate tissue repair, boost circulation, and reduce pain. Learn the mechanisms, evidence, and what to expect.

Acupuncture

Acupuncture uses thin needles at specific body points to modulate the nervous system, reduce inflammation, and influence pain signaling. Evidence, risks, and practical guidance.

Biofeedback

Biofeedback uses sensors to display physiological data like heart rate, muscle tension, and brain waves, training conscious control over normally automatic body functions.

Bioidentical Hormone Replacement Therapy

Bioidentical hormone replacement therapy uses hormones structurally identical to human hormones to address age-related decline, with evidence on benefits, risks, and protocols.

Blood Irradiation Therapy

Blood irradiation therapy exposes blood to ultraviolet or laser light to modulate immune function and reduce infections. Here is how it works and what the evidence shows.

Carbon Dioxide Therapy

Carbon dioxide therapy uses CO2 gas to improve blood flow, oxygen delivery, and tissue repair. Learn how it works, what to expect, and what the evidence shows.

Chelation Therapy

Chelation therapy uses synthetic or natural agents to bind and remove heavy metals from the body. Mechanisms, evidence, risks, and what to expect.

Chiropractic Care

Chiropractic care uses manual spinal adjustments to restore joint mobility and nervous system function, with evidence on pain relief, posture, and long-term musculoskeletal health.

Cold Plunge

Cold plunge involves deliberate immersion in cold water to activate stress-response pathways, shift circulation, and influence recovery. Here is what the evidence shows.

Colon Hydrotherapy

Colon hydrotherapy uses warm water to flush the large intestine. Learn how it works, what the session involves, and what the evidence actually supports.

Compression Therapy

Compression therapy uses mechanical pressure to enhance venous return, reduce fluid buildup, and accelerate recovery, with evidence across clinical and performance contexts.

Contrast Therapy

Contrast therapy alternates hot and cold exposure to drive vascular changes, reduce inflammation, and speed recovery. Here is how it works and what to expect.

Craniosacral Therapy

Craniosacral therapy uses gentle touch on the skull and spine to influence cerebrospinal fluid rhythm, with evidence on pain relief, nervous system regulation, and recovery.

Cryotherapy

Cryotherapy exposes the body to extreme cold to reduce inflammation, speed recovery, and activate stress-response pathways. Here is how it works and what the evidence shows.

Cupping Therapy

Cupping therapy uses suction on the skin to decompress tissue, alter local blood flow, and modulate pain signaling. Here is how it works and what the evidence shows.

Dry Needling

Dry needling uses thin filament needles inserted into myofascial trigger points to reduce pain and restore muscle function. Mechanism, evidence, and what to expect.

EBO2 (Extracorporeal Blood Oxygenation and Ozonation)

EBO2 filters blood outside the body while exposing it to ozone and oxygen, targeting oxidative balance and circulation. Here is how it works and what the evidence says.

Electroacupuncture

Electroacupuncture applies mild electrical current through acupuncture needles to modulate pain pathways and nervous system function. Mechanisms, evidence, and what to expect.

Float Therapy

Float therapy uses a buoyant, lightless tank to reduce sensory input and lower stress hormones, with effects on pain, sleep, and nervous system regulation.

Grounding (Earthing)

Grounding, or earthing, involves direct physical contact with the Earth's surface. Learn the proposed mechanisms, evidence on inflammation and sleep, and how to practice it.

Hormone Replacement Therapy

Hormone replacement therapy restores declining hormones using exogenous formulations. Learn how HRT works, who it applies to, and what the evidence shows.

Hyperbaric Oxygen Therapy

Hyperbaric oxygen therapy delivers pure oxygen at above-normal pressure to boost tissue oxygenation, supporting wound healing, recovery, and cellular repair.

Infrared Sauna Therapy

Infrared sauna therapy uses light wavelengths to heat the body directly, promoting sweating, circulation, and cellular stress responses relevant to longevity.

Intravenous Laser Blood Irradiation

Intravenous laser blood irradiation delivers low-level laser light directly into the bloodstream via a fiber optic catheter, aiming to modulate circulation and cellular function.

IV Glutathione

IV glutathione delivers the body's master antioxidant directly into the bloodstream, bypassing digestive absorption limits. Mechanisms, evidence, and what to expect.

IV Therapy

IV therapy delivers vitamins, minerals, and fluids directly into the bloodstream, bypassing digestion. Learn how it works, what the evidence shows, and what to expect.

IV Vitamin C (High-Dose)

IV vitamin C delivers gram-level ascorbic acid directly into the bloodstream, bypassing gut absorption limits. Here is how it works, what the evidence shows, and what to expect.

Ketamine Therapy

Ketamine therapy uses sub-anesthetic doses of a dissociative anesthetic to treat depression, PTSD, and chronic pain by modulating glutamate signaling and neural plasticity.

Low-Level Laser Therapy

Low-level laser therapy uses focused light at specific wavelengths to stimulate cellular repair and reduce inflammation, with evidence across pain, wound healing, and neurological applications.

Lymphatic Drainage

Lymphatic drainage uses gentle manual or mechanical techniques to move fluid through the lymphatic system, supporting immune function and waste clearance.

Manual Lymphatic Drainage

Manual lymphatic drainage uses gentle, rhythmic massage to move lymph fluid through the body, supporting immune function and reducing tissue swelling.

MDMA-Assisted Therapy

MDMA-assisted therapy combines the empathogen MDMA with guided psychotherapy sessions to treat PTSD and trauma, with evidence from Phase 3 clinical trials.

Microcurrent Therapy

Microcurrent therapy uses electrical currents below the threshold of sensation to support tissue repair, reduce pain, and influence cellular energy production.

Molecular Hydrogen Therapy

Molecular hydrogen therapy uses dissolved H2 gas as a selective antioxidant, targeting harmful reactive oxygen species while sparing beneficial ones.

Moxibustion

Moxibustion uses burning dried mugwort near the skin to stimulate circulation and immune function. Learn the mechanisms, evidence, and what to expect.

Myers' Cocktail

Myers' Cocktail is an intravenous infusion of magnesium, calcium, B vitamins, and vitamin C used to bypass digestive absorption. Here is how it works and what the evidence shows.

Myofascial Release

Myofascial release applies sustained pressure to connective tissue restrictions, restoring mobility and reducing pain. Mechanisms, evidence, and what to expect.

NAD+ Therapy

NAD+ therapy delivers nicotinamide adenine dinucleotide via IV or other routes to support cellular energy and repair. Here is the evidence, cost, and what to expect.

Nanomedicine

Nanomedicine uses engineered structures at the nanometer scale for targeted drug delivery, diagnostics, and tissue repair, with implications for aging and disease.

Neural Therapy

Neural therapy uses local anesthetic injections at specific body sites to reset disrupted nerve signaling, addressing chronic pain and autonomic dysfunction.

Neurofeedback

Neurofeedback uses real-time EEG monitoring to train brainwave patterns, targeting focus, sleep, and stress resilience. Here is how it works and what the evidence shows.

Normatec Recovery

Normatec recovery uses sequential pneumatic compression to enhance lymphatic drainage and reduce muscle soreness, with details on how it works and what to expect.

Ozone Therapy

Ozone therapy introduces medical-grade ozone (O3) into the body to modulate oxidative stress and immune function. Here is how it works, what to expect, and what the evidence shows.

Photodynamic Therapy

Photodynamic therapy uses light-activated compounds to destroy targeted cells. Learn how it works, what conditions it treats, and what the evidence shows.

Psilocybin Therapy

Psilocybin therapy uses the active compound in psychedelic mushrooms in a clinical setting, targeting serotonin receptors to address depression, anxiety, and rigidity of thought.

Psychedelic-Assisted Therapy

Psychedelic-assisted therapy combines controlled doses of psychedelic compounds with guided psychotherapy to address mental health conditions and promote neuroplasticity.

Pulsed Electromagnetic Field Therapy

PEMF therapy uses low-frequency electromagnetic pulses to influence cellular repair and inflammation, with evidence ranging from FDA-cleared uses to exploratory longevity claims.

Red Light Therapy

Red light therapy uses specific wavelengths of light to stimulate mitochondrial function and cellular repair. Here is how it works and what the research shows.

Rolfing (Structural Integration)

Rolfing is a hands-on bodywork system that reorganizes connective tissue to improve posture, movement, and chronic pain. Here is how it works and what to expect.

Shockwave Therapy

Shockwave therapy uses acoustic pressure waves to stimulate tissue repair, reduce pain, and promote blood vessel formation. Here is how it works and what evidence supports it.

Silver Hydrosol Therapy

Silver hydrosol therapy uses ultrafine silver particles suspended in water to support immune function, with a look at mechanisms, evidence, and safety.

Stellate Ganglion Block

A stellate ganglion block injects local anesthetic near the neck's sympathetic nerve cluster to reset overactive fight-or-flight signaling and reduce chronic stress.

Structural Therapy

Structural therapy uses manual and movement-based techniques to restore alignment, improve fascial health, and reduce chronic pain tied to aging.

Thyroid Optimization

Thyroid optimization adjusts thyroid hormone levels to support metabolism, energy, and longevity, using targeted testing and individualized protocols.

Transcranial Direct Current Stimulation

Transcranial direct current stimulation (tDCS) uses weak electrical current applied to the scalp to modulate brain activity, with research spanning cognition, mood, and neuroplasticity.

Transcranial Magnetic Stimulation

Transcranial magnetic stimulation uses focused magnetic pulses to alter neural activity, with applications in depression, cognition, and neurological recovery.

Trigger Point Therapy

Trigger point therapy targets hyperirritable knots in muscle tissue to relieve referred pain, restore range of motion, and support musculoskeletal longevity.

Ultraviolet Blood Irradiation

Ultraviolet blood irradiation exposes a small volume of drawn blood to UV light before reinfusion, aiming to modulate immune function and reduce infections.

Vagus Nerve Stimulation

Vagus nerve stimulation activates the body's longest cranial nerve to regulate inflammation, heart rate, and stress response. Mechanisms, evidence, and practical options.

Vibroacoustic Therapy

Vibroacoustic therapy uses low-frequency sound vibrations delivered through specialized surfaces to influence the nervous system, pain perception, and stress.

Visceral Manipulation

Visceral manipulation is a manual therapy targeting organ mobility and fascial restrictions. Learn how it works, what the evidence says, and what to expect.

Whole Body Vibration Therapy

Whole body vibration therapy uses mechanical oscillations to stimulate muscles, bones, and circulation. Learn how it works, what evidence supports it, and who benefits.

Latest News in Therapies and Protocols

LT WireMay 7, 2026

Restore Hyper Wellness kicks off NAD Month to educate on IV, IM therapies

Restore Hyper Wellness is promoting NAD supplementation through IV and intramuscular delivery formats, capitalizing on significant year-over-year increases in consumer search interest for NAD-related therapies. The initiative positions NAD precursors and direct NAD administration as tools for cellular energy optimization, though clinical evidence supporting broad longevity claims remains limited.

Longevity.TechnologyMar 16, 2026

Engineering longevity with the ZEUGMA hyperbaric chamber

Hyperbaric oxygen therapy, traditionally confined to clinical medicine, is being deployed in performance and longevity settings through chambers like ZEUGMA, which operate at pressures enabling oxygen to dissolve into plasma at concentrations far exceeding atmospheric levels. The mechanism addresses tissue oxygen delivery and cellular repair, though evidence for durable benefits in healthy individuals remains under investigation.

Longevity.TechnologyApr 29, 2026

Nuchido announced as Catalyst Partner for The Longevity Show

Nuchido addresses NAD+ decline through targeted restoration of the salvage pathway rather than simple precursor replacement, supported by randomized controlled human trials demonstrating improvements in inflammation, glycation, and biological age markers. This systems-biology approach represents a maturation of the NAD+ intervention landscape toward mechanistic rather than marketing-driven solutions.

LT WireMay 6, 2026

Niagen Bioscience launches Niagen Plus telehealth platform

Niagen Bioscience launched Niagen Plus, a telehealth platform delivering prescription-only nicotinamide riboside (Niagen) via at-home subcutaneous injection. The injectable route is positioned to bypass first-pass hepatic metabolism and improve tissue bioavailability compared to oral administration.

Longevity.TechnologyFeb 6, 2026

Designing therapies patients can live with

Light-activated photodynamic therapy for cutaneous T-cell lymphoma demonstrates a treatment design principle critical to chronic disease management: therapies must be engineered for decades of safe, repeatable use rather than optimized solely for efficacy. For conditions that persist across a lifespan, cumulative toxicity and patient burden become as clinically significant as the primary disease.

Nature - npj AgingApr 3, 2026

Psilocybin and human longevity

Psilocybin demonstrates measurable effects on lifespan and healthspan markers in preclinical models, operating through neuroplasticity pathways and stress-response modulation. The compound's capacity to alter consciousness-linked neural signaling raises questions about its role in longevity pathways previously associated with psychological resilience and systemic stress tolerance.